Highlights for doxycycline

  1. Doxycycline oral tablet is available as both a generic and brand-name drug. Brand names: Acticlate, Doryx, Doryx MPC.
  2. Doxycycline comes in three oral forms: a tablet, a capsule, and a suspension. It also comes as a solution for injection, which is only given by a healthcare provider.
  3. Doxycycline oral tablet is used to treat infections and severe acne. It’s also used to prevent malaria.

Doxycycline side effects

Doxycycline oral tablet can cause side effects. Some are more common, and some are serious.

More common side effects

The more common side effects of doxycycline can include:

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

This drug does not cause drowsiness.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Important warnings

What is doxycycline?

Doxycycline oral tablet is a prescription drug that’s available as the brand-name drugs Acticlate, Doryx, and Doryx MPC. It’s also available as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

Doxycycline tablets come in immediate-release and delayed-release forms. Doxycycline also comes in two other oral forms: capsule and solution. In addition, doxycycline comes in a solution for injection, which is only given by a healthcare provider.

Why it’s used

Doxycycline is used to treat bacterial infections. These can include some sexually transmitted diseases, skin infections, eye infections, respiratory infections, and more. It is also used as an add-on treatment for severe acne and to prevent malaria in people who plan to travel to areas with certain strains of malaria.

This drug may be used as part of a combination therapy. This means you may need to take it with other medications.

How it works

Doxycycline belongs to a class of drugs called tetracyclines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

This drug works by blocking a bacterial protein from being made. It does this by binding to certain units of the protein. This stops the protein from growing and treats your infection.

Doxycycline may interact with other medications

Doxycycline oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with doxycycline are listed below.

Drugs that you should not use with doxycycline

Do not use these drugs with doxycycline. Doing so can cause dangerous effects in your body. Examples of these drugs include:

Interactions that can make your drugs less effective

When you take doxycycline with certain drugs, doxycycline may not work as well to treat your condition. This is because the amount of doxycycline in your body may be decreased. Examples of drugs that can cause this type of interaction include:

Interactions that can increase side effects

Taking doxycycline with certain medications raises your risk of side effects from these drugs. An example of a drug that could cause this type of interaction is:

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Doxycycline warnings

Doxycycline oral tablet comes with several warnings.

Allergy warning

Doxycycline can cause a severe allergic reaction. Symptoms can include:

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it or other tetracyclines. Taking it again could be fatal (cause death).

Food interaction warning

Foods that contain calcium may block the amount of this drug that’s absorbed by your body. This means it may not work as well to treat your condition. Some foods that are high in calcium include milk and cheese. If you eat or drink these items, do so at least one hour before taking this drug or one hour after taking this drug.

Warnings for people with certain health conditions

For women of childbearing age who are overweight: You have a higher risk of high blood pressure inside of your skull from this drug. Ask your doctor if this drug is right for you.

For people with a history of intracranial hypertension:You have a higher risk of high blood pressure inside of your skull from this drug. Ask your doctor if this drug is right for you.

Warnings for other groups

For pregnant women: There are no adequate studies on the use of doxycycline in pregnant women.

Talk to your doctor if you’re pregnant or planning to become pregnant. Ask your doctor to tell you about the specific risk to the pregnancy. This drug should only be used if the potential risk to the pregnancy is acceptable given the drug’s potential benefit. Call your doctor right away if you become pregnant while taking this drug.

For women who are breastfeeding: Doxycycline passes into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects.

For children: This drug may cause tooth discoloration at the time teeth are developing.

This drug should not be used in children who are 8 years of age or younger unless the potential benefit outweighs the risk. In these children, its use is recommended for the treatment of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever, and when no other treatments are available or have been shown to work.

How to take doxycycline

This dosage information is for doxycycline oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

The dosage information below is for the conditions that this drug is most often prescribed to treat. This list may not contain all conditions that your doctor can prescribe this drug for. If you have questions about your prescription, talk with your doctor.

Forms and strengths

Generic: Doxycycline

Brand: Acticlate

Brand: Doryx

Brand: Doryx MPC

Dosage for infection

Adult dosage (ages 18–64 years)

Generic immediate-release:

Doryx and Acticlate:

Doryx MPC:

Child dosage (ages 8–17 years)

Generic immediate-release and Acticlate:

Doryx:

Doryx MPC:

Child dosage (ages 0–7 years)

It has not been confirmed that this drug is safe and effective for use in people who are younger than 8 years.

Senior dosage (ages 65 years and older)

Your doctor may start you on a lowered dosage or a different schedule. This can help keep levels of this drug from building up too much in your body.

Dosage for malaria prevention

Adult dosage (ages 18-64 years)

Generic immediate-release, Doryx, and Acticlate:

Doryx MPC:

Child dosage (ages 8–17 years)

Generic immediate-release, Doryx, and Acticlate:

Doryx MPC:

Child dosage (ages 0–7 years)

It has not been confirmed that this drug is safe and effective for use in children younger than 8 years.

Senior dosage (ages 65 years and older)

Your doctor may start you on a lowered dosage or a different schedule. This can help keep levels of this drug from building up too much in your body.

Take as directed

Doxycycline oral tablet is used for short-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your infection will likely not go away. If you’re taking it for malaria prevention, you won’t be protected against certain infections. This may be fatal.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. You may feel better before you finish your course of treatment, but you should keep taking your medication as directed. Skipping doses or failing to complete the full course of treatment may reduce how well your treatment works. It may also cause antibiotic resistance. This means that your infection won’t respond to doxycycline or other antibiotics in the future.

If you take too much: You could have dangerous levels of the drug in your body and experience more side effects. If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take your dose as soon as you remember. If you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. Doing so could result in dangerous side effects.

How to tell if the drug is working: Your symptoms may start to improve and you may feel better.

Important considerations for taking this doxycycline

Keep these considerations in mind if your doctor prescribes doxycycline oral tablet for you.

General

Storage

Travel

When traveling with your medication:

Sun sensitivity

This drug can make your skin more sensitive to the sun and increase your risk of sunburn. Avoid the sun if you can. If you can’t, be sure to apply sunscreen and wear protective clothing.

Insurance

Many insurance companies require a prior authorization for this drug. This means your doctor may need to get approval from your insurance company before your insurance company will pay for the prescription.

Are there any alternatives?

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: EDPHARMACY has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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